On the cover: Retinal vasculature in a GFP⁺chimeric mouse subjected to laser vessel occlusion injury. Mice underwent injection within the vitreous of liposomes containing plasmids expressing insulin-like growth factor binding protein-3. Three weeks after injection, the mice were sacrificed and retinal flatmounts prepared. The vessels were labeled with rhodamine agglutinin (red) and imaged using fluorescence microscopy. Enhanced incorporation of GFP⁺ progenitor cells (green) into the injured retinal vessels is shown. IGFBP-3’s protective effects on the vasculature may be, in part, the result of its ability to recruit endothelial progenitor cells to sites of vascular injury. See related article, page 897.